Comparative analysis of IL6 and IL6 receptor gene polymorphisms in mastocytosis
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چکیده
منابع مشابه
Associations of IL6 polymorphisms with lung function decline and COPD.
BACKGROUND Interleukin-6 (IL6) is a pleiotropic pro-inflammatory and immunomodulatory cytokine which probably plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). There is a functional single nucleotide polymorphism (SNP), -174G/C, in the promoter region of IL6. It was hypothesised that IL6 SNPs influence susceptibility for impaired lung function and COPD...
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Several lines of evidence indicate a causal role of the cytokine interleukin (IL)-6 in the development of type 2 diabetes in humans. Two common polymorphisms in the promoter of the IL-6 encoding gene IL6, -174G>C (rs1800795) and -573G>C (rs1800796), have been investigated for association with type 2 diabetes in numerous studies but with results that have been largely equivocal. To clarify the r...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2012
ISSN: 0007-1048
DOI: 10.1111/bjh.12086